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A large randomised controlled trial of thrombolysis with intravenous recombinant tissue plasminogen activator (rt-PA) for acute ischaemic stroke within 6 hours

Final Number of Patients Recruited
3035

Follow breaking news about the trial on Twitter: @IST_3

IST-3 Statistical analysis plan now finalised  - see details

IST-3 baseline data paper now  published!

 PDF can be downloaded free from

http://www.trialsjournal.com/content/12/1/252/abstract

Slides from presentation at UK Stroke Forum available here

link to presentation


Please use this link to logon and see slides from IST-3 collaborators meeting, Glasgow, 30th November 2011

Please use this link to logon to see the trial results dissemination strategy,
which lists all the meetings at which we aim to present different aspects of the trial's results.

Please email any additions or corrections to ist3@skull.dcn.ed.ac.uk

 

Slides from Peter Sandercock's talk at the European Stroke Conference, Hamburg on Friday 27th May

Can patients be too mild, too severe or too old for thrombolysis?
 

Slides from the IST-3 collaborators meeting are available in the login area of the site
 

Two papers on IST-3 from the International Journal of Stroke
 

Where are we now with intravenous thrombolysis for acute ischaemic stroke?
(pages 381-382)

Peter Sandercock, Joanna Wardlaw and Richard Lindley.
 

How many patients might receive thrombolytic therapy in the light of the ECASS-3 and IST-3 data?

Jan Bembenek, Adam Kobayashi, Peter Sandercock and Anna Czlonkowska.

 

If you would like a copy of either article, please email peter.sandercock@ed.ac.uk
 
Listen to the podcast about IST-3 
 http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1747-4949/homepage/podcasts.htm!
 
 


Download a poster to display in your Emergency Department
Informs who to contact about acute stroke patients
who may be eligible for IST-3
(In .doc format so you can add local details)

Improve your acute stroke imaging interpretative skillsImprove your acute stroke imaging interpretative skills!

See- BASP CT Training Series  
 

Are you participating in IST-3 and interested in perfusion or angiographic imaging?

Click here to find out more about participating in IST-3 perfusion/angiography imaging study


ACCESS Study - The Acute Cerebral CT Evaluation Study

For additional on-line training (with a certificate issued on completion of each module) in core competencies in stroke care (with basic modules on thrombolysis) http://www.stroketraining.org.
 Advanced modules on thrombolysis now available
 

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The IST-3 protocol is now published in full at BMC Trials,
as an open-access publication, at http://www.trialsjournal.com/content/9/1/37
Please feel free to link to it from your personal or institutional website

 

 

CONTACT

The IST-3 Trial Co-ordinating Centre
Neuroscience Trial Unit
Bramwell Dott Building
Western General Hospital
Crewe Road
Edinburgh, UK
EH4 2XU

Tel:+44 (0)131 537 2793
Fax: +44 (0)131 332 5150
ist3@skull.dcn.ed.ac.uk

Our WebServer is maintained by David Perry: dnap@skull.dcn.ed.ac.uk
This site is maintained by Vera Soosay: ves@skull.dcn.ed.ac.uk
and was last update on 17th January 2012