| Postal Address | Medical and Radiological Sciences (Medical Physics), University of Edinburgh, Western General Hospital, Crewe Rd, Edinburgh, EH4 2XU, UK |
| Research overview | Dr. Bastin’s primary research interest is in the development of magnetic resonance imaging (MRI) acquisition methods and post-processing techniques and their application to the study of the pathophysiology of diseases of the human brain. Specific areas of interest include: -
Diffusion tensor MRI
- Dynamic susceptibility contrast perfusion MRI
- Magnetization transfer MRI
- Quantitative spin-lattice relaxation (T1) measurement
- Numerical MRI signal modelling and simulation
- Application to ischaemic stroke, brain tumours, ageing, schizophrenia, bipolar disorder and depression
Dr Bastin has authored over 40 articles in leading peer-review journals. He currently supervises or co-supervises three PhD students and is a principal investigator or co-applicant on approximately £6M of grant funding. |
| Recent Publications | - Karaszewski B; Wardlaw JM; Marshall I; Cvoro V; Wartolowska K; Haga K; Armitage PA; Bastin ME; Dennis MS; Measurement of brain temperature with magnetic resonance spectroscopy in acute ischemic stroke. Ann Neurol : 2006, Vol No:, Issue No:, ISSN:0364-5134.
- Marshall I; Karaszewski B; Wardlaw JM; Cvoro V; Wartolowska K; Armitage PA; Carpenter T; Bastin ME; Farrall A; Haga K; Measurement of regional brain temperature using proton spectroscopic imaging: validation and application to acute ischemic stroke. Magn Reson Imaging : 2006, Vol No:24, Issue No:6, ISSN:0730-725X.
- Deary IJ; Bastin ME; Pattie A; Clayden JD; Whalley LJ; Starr JM; Wardlaw JM; White matter integrity and cognition in childhood and old age. Neurology : 2006, Vol No:66, Issue No:4, ISSN:1526-632X.
- Sinha S; Bastin ME; Wardlaw JM; Armitage PA; Whittle IR; Effects of dexamethasone on peritumoural oedematous brain: a DT-MRI study. J Neurol Neurosurg Psychiatry : 2004, Vol No:75, Issue No:11, ISSN:0022-3050.
- Munoz MS; Bastin ME; Armitage PA; Farrall AJ; Carpenter TK; Hand PJ; Cvoro V; Rivers CS; Wardlaw JM; Temporal evolution of water diffusion parameters is different in grey and white matter in human ischaemic stroke. J Neurol Neurosurg Psychiatry : 2004, Vol No:75, Issue No:12, ISSN:0022-3050.
- Burns J; Job D; Bastin ME; Whalley H; Macgillivray T; Johnstone EC; Lawrie SM; Structural disconnectivity in schizophrenia: a diffusion tensor magnetic resonance imaging study. Br J Psychiatry : 2003, Vol No:182, Issue No:, ISSN:0007-1250.
- Bastin ME; Sinha S; Farrall AJ; Wardlaw JM; Whittle IR; Diffuse brain oedema in idiopathic intracranial hypertension: a quantitative magnetic resonance imaging study. J Neurol Neurosurg Psychiatry : 2003, Vol No:74, Issue No:12, ISSN:0022-3050.
- Bastin ME; Sinha S; Farrall AJ; Wardlaw JM; Whittle IR; Diffuse brain oedema in idiopathic intracranial hypertension: a quantitative magnetic resonance imaging study. J Neurol Neurosurg Psychiatry : 2003, Vol No:74, Issue No:12, ISSN:0022-3050.
- Bastin ME; Sinha S; Farrall AJ; Wardlaw JM; Whittle IR; Diffuse brain oedema in idiopathic intracranial hypertension: a quantitative magnetic resonance imaging study. J Neurol Neurosurg Psychiatry : 2003, Vol No:74, Issue No:12, ISSN:0022-3050.
- Wardlaw JM; Keir SL; Bastin ME; Armitage PA; Rana AK; Is diffusion imaging appearance an independent predictor of outcome after ischemic stroke?. Neurology : 2002, Vol No:59, Issue No:9, ISSN:0028-3878.
- Bastin ME; Le RP; On the application of a non-CPMG single-shot fast spin-echo sequence to diffusion tensor MRI of the human brain. Magn Reson Med : 2002, Vol No:48, Issue No:1, ISSN:0740-3194.
- Armitage PA; Bastin ME; Utilizing the diffusion-to-noise ratio to optimize magnetic resonance diffusion tensor acquisition strategies for improving measurements of diffusion anisotropy. Magn Reson Med : 2001, Vol No:45, Issue No:6, ISSN:0740-3194.
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